Resolution:
## Figure 2.
Effect of an AGE-modified type I collagen matrix on UMR106 cell proliferation and
spreading. UMR106 osteosarcoma cells were cultured on an unmodified collagen matrix
or an AGE-collagen matrix for 24 hours at 37°C. Cell proliferation was evaluated by
microscopically counting cells stained with Giemsa, at a magnification of 400X. Cellular
spreading was also estimated microscopically, as the number of cells possessing at
least two comers. Results are given as the number of cells counted per field, and
are expressed as the mean ± SEM. Differences between collagen vs. AGE-collagen are
as follows:
^{*} p < 0.001
McCarthy |