|Summary of changes in several important parameters involved in high glucose induced protein aggregation in ZDF brain and the effect of NaHS on them|
|Parameters analyzed||ZDF brain||NaHS + ZDF brain|
|Protein synthesis (mTOR, S6)||↑||↓|
|Autophagy||↓ (LC3-II↓, LC3-I↑)||↑ (LC3-II↓, LC3-I↓)|
|Tau and p-tau||↑||↓|
ZDF brain was compared to lean brain as control and NaHS treated ZDF brain was compared to ZDF brain as control. The arrows indicate the changes in each parameter.
Talaei et al.
Talaei et al. BMC Cell Biology 2014 15:1 doi:10.1186/1471-2121-15-1