Table 2

Summary of changes in several important parameters involved in high glucose induced protein aggregation in ZDF brain and the effect of NaHS on them
Parameters analyzed ZDF brain NaHS + ZDF brain
ROS levels
Protein aggregates
Protein synthesis (mTOR, S6)
FABP
Thiols
CBS
CML expression
UB-proteins
Autophagy ↓ (LC3-II↓, LC3-I↑) ↑ (LC3-II↓, LC3-I↓)
Tau and p-tau
Fibronectin

ZDF brain was compared to lean brain as control and NaHS treated ZDF brain was compared to ZDF brain as control. The arrows indicate the changes in each parameter.

Talaei et al.

Talaei et al. BMC Cell Biology 2014 15:1   doi:10.1186/1471-2121-15-1

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