Evident conservation of the tau mutant region across species. A) Multiple sequence alignment of part of the kinase domain of CK1 isoforms from circadian model organisms. An arrowhead indicates location of the tau mutant from Syrian hamster. B) Consensus logo generated from CK1 isoforms of circadian model organisms, for the region around the tau mutation.
van Ooijen et al. BMC Cell Biology 2013 14:46 doi:10.1186/1471-2121-14-46