Additional file 7: Figure S7.
Proteasome RNAi induces autophagy in well-fed cells. A-H) Knockdown of Prosα1 (A, B), Prosα5 (C, D), Prosβ2 (E, F), and Rpt1 (G, H) induces the formation of LTR-positive autolysosomes in fat body cell clones (marked by Lamp1-GFP expression) compared to surrounding non-GFP control cells in well fed larvae (A, C, E, G), and also leads to increased generation of Atg8a-positive autophagosomes (B, D, F, H) in fat body cell clones of well fed larvae. Boxed areas in A-H are shown enlarged. Scale bar in A equals 20 μm for A-H.
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Lőw et al. BMC Cell Biology 2013 14:29 doi:10.1186/1471-2121-14-29