Confocal optical sections displaying the nuclear positioning of chromosomes 5, 13, 17 and X in porcine brain, kidney, and lung tissue. The insets show nuclei that have been enlarged for greater detail from other fields of view. Whole chromosome painting probes were labelled with biotin and detected using streptavidin conjugated to fluorescein isothiocyanate (green) and the nuclei were counterstained with propidium iodide (red). Bar, 10 μm.
Foster et al. BMC Cell Biology 2012 13:30 doi:10.1186/1471-2121-13-30