Knockdown of ceMTM3 does not aggravate the abnormalities of muscle wasting in atg-18 mutant worms. VC893 atg-18 mutant worms were cultured on NGM plates containing E. coli cells carrying vector control or ceMTM3 RNAi from the time they were hatched from eggs. A. Moving tracks of day 5 N2 and VC893 worms cultured under the normal condition. B. Alexa Fluor 568 phalloidin staining of muscle fibers in control and ceMTM3 RNAi-treated worms of indicated ages. In comparison with normal N2 worms shown in Figure 1, VC893 worms displayed dimmer and less organized muscle fiber staining.
Yu et al. BMC Cell Biology 2012 13:28 doi:10.1186/1471-2121-13-28