Figure 1.

C. elegans ERL-1 is a homologue of human erlin proteins. ClustalW alignment of C.elegans (Ce) ERL-1 and human (Hs) erlin-1 and erlin-2. Transmembrane domains (predicted by TMAP) are marked by blue boxes, N-glycosylation site is marked by green box, F305/303 required for oligomerization is marked by red box. The SPFH domain (pfam01145) is indicated by black dotted lines.