Additional file 4.
Figure S3. CHX increases p53 expression in HD matrix. MTLn3 breast cancer cells were allowed to invade into HD matrices for 24 h before treatment with 1 μM and 3 μM MS-275, 10 μg/ml of cycloheximide (CHX) and both CHX and MS-275 and cells were grown for further 24 h. Treatment of MS-275 at both concentrations did not affect the expression of p53 transcript in HD matrix. However, treatment of CHX increases the p53 expression. Bar indicates standard error from two biological samples and experiments were performed two times. 1-way ANOVA followed by post-hoc Tukey’s test indicating significant difference at either * p < 0.05 or ** p < 0.01.
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Raviraj et al. BMC Cell Biology 2012 13:12 doi:10.1186/1471-2121-13-12