Table 1

Predicted sequence variation in Klar^MW

AA #

Observed change

Exon affected

Notes

633

Ser to Thr

7

a, b

1013

Ser to Thr

9

a, b

1210

Ser to Ala

11

a, c

1358

Asp to Glu

11

a, b, c

1366

Ser to His

11

a, b, c

1510

Thr to Ser

13

a, b, c

1577

Ile to Asn

14

a, b, c

Frame shift

See Fig. 1A

15ext

1887

Thr to Ser

17

a, b

1909

Ser to Ala

17

a, b

The protein coding exons of klar^MW were sequenced, and the predicted protein sequence was compared to the wild-type Klar sequence available on FlyBase. The position of the sequence change is given relative to the protein sequence of the originally reported Klar α protein [24]. Exons numbering follows the convention established previously [22]. Notes indicate if a particular amino acid change is shared with other klar alleles.

^a present in Klar^Z

^b present in a wild-type Klar α cDNA (GenBank AAD43129, as reported in [24])

^c present in various wild-type klar alleles (S. Jangi, Y. Guo, MAW, unpublished observations)

Yu et al. BMC Cell Biology 2011 12:9   doi:10.1186/1471-2121-12-9