Activation of ERK and p38 MAPK but not JNK signaling pathways by AGE-BSA. Representative western blots of ERK, phosphorylated ERK, p38 MAPK, phosphorylated p38 MAPK, JNK, and phosphorylated JNK in cells treated with AGE-BSA for 2 (A) and 6 hours (B). Phosphorylation of ERK and p38 MAPK was activated dose-dependently but no such effect was seen for JNK.
Wang et al. BMC Cell Biology 2011 12:19 doi:10.1186/1471-2121-12-19