Dose-dependent reduction in viability of cells treated with AGE-BSA, as detected by MTT assay. Note a dose-dependent reduction is seen in cells treated with AGE-BSA for 24 hours. For each dose of treatment, the relative level of the total amount of cells is shown in the histogram. The relative viability of cells significantly reduced to 94.2 ± 0.2%, 90.2 ± 1.4%, and 81.6 ± 0.8% post exposure to 100 μg/ml, 250 μg/ml, and 500 μg/ml, respectively. *, p < 0.05 compared to the untreated cells.
Wang et al. BMC Cell Biology 2011 12:19 doi:10.1186/1471-2121-12-19