Effects of Crb2a extracellular domain-containing constructs on endogenous Crumbs proteins. (A-D"') Confocal z-projections of 6 d rods labeled with GFP (green), panCrb (blue) and anti-HA (red) antibodies. (A, A') Wild-type rods. (B-B"') Crb2aFL transgenic rods. Inset in B shows fine processes emerging from the inner segment. Bracket in B' indicates a region of strong panCrb labeling that is weakly labeled by anti-HA antibodies. (C-C"') Crb2aExtra_TM transgenic rods. (D-D"') Crb2aExtra_Secr transgenic rods. Scale bar, 5 μm.
Hsu and Jensen BMC Cell Biology 2010 11:60 doi:10.1186/1471-2121-11-60