Email updates

Keep up to date with the latest news and content from BMC Cell Biology and BioMed Central.

Open Access Research article

Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2

Peixiang Wang1 and Tianru Jin12345*

Author Affiliations

1 Div. of Cell and Molecular Biology, Toronto General Research Institute, University Health Network, 10-354 Toronto Medical Discovery Tower, The MaRS Building, 101 College St., Toronto, Ontario, M5G 1L7, Canada

2 Dept. of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5 S 1A8, Canada

3 Dept. of Medicine, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada

4 Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5 S 1A8, Canada

5 Dept. of Nutrition, School of Public Health, Sun Yat-Sen University, 74 2nd Zhongshan Road, Guangzhou, Guangdong Province, 510080, PR China

For all author emails, please log on.

BMC Cell Biology 2010, 11:56  doi:10.1186/1471-2121-11-56

Published: 16 July 2010

Additional files

Additional file 1:

Forsklin/IBMX treatment causes Oct-1-EGFP shuttling from nuclear to cytoplasm. Treating the InR1G9 cell line with forskolin/IBMX led to increased Oct-1-EGFP content in the cytosol.

Format: PDF Size: 93KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

cAMP promoting agents cause Oct-1-EGFP shuttling from nuclear to cytoplasm. Both membrane permeable cAMP analogue and the Epac pathway specific cAMP analogue increased Oct-1-EGFP content in the cytosol.

Format: PDF Size: 151KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data