Table 1

Transforming activity of HCCR-1 in HEK-293 cells

Transfected DNA source

Foci/μg DNA*

Transformation efficiency**

95% confidence intervals

HCCR-1

13/15

0.9

11.2-13.8

Wild-type ras

18/15

1.2

16.0-19.1

Vector alone

0/15

0

-

*HEK-293cells (3 × 10⁵ cells) were transfected with 5 μg of DNA obtained from indicated source. The results reported here were derived from 3 independent experiments.

**Transformed cell aggregates, foci, were counted by visual examination starting 2-3 weeks after transfection and the transformation efficiencies (i.e., the number of foci per microgram of DNA transfected) were determined.

Ha et al. BMC Cell Biology 2010 11:49   doi:10.1186/1471-2121-11-49