Islet-like cell clusters release insulin in response to glucose in vitro. After pancreatic induction, the amount of insulin in the culture media was measured by ELISA after the cells (clones 27 and 45) were exposed to different concentrations of glucose. One-way ANOVA showed significant differences between groups (p < 0.05). The asterisks denote a significant difference between two groups.
Bi et al. BMC Cell Biology 2010 11:46 doi:10.1186/1471-2121-11-46