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Open Access Research article

CC3/TIP30 affects DNA damage repair

Sylvia Fong, Frank King and Emma Shtivelman*

Author Affiliations

BioNovo Inc, 5858 Horton Street, Emeryville 94608, CA, USA

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BMC Cell Biology 2010, 11:23  doi:10.1186/1471-2121-11-23

Published: 7 April 2010

Additional files

Additional file 1:

Summary of changes induced in cell lines by manipulation of CC3 expression. The Table shows list of cell lines used in the study including the status of endogenous CC3 expression, the effects of manipulating CC3 levels on cell proliferation and survival, and changes in expression levels of DDB2, p21CIP, FOS and NXN in response to changes in CC3 levels.

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Additional file 2:

List of genes differentially expressed in untreated U373neo cells versus U373cc3 cells. The Table shows results of comparative expression array analysis of the glioblastoma cells U373 stably transfected with CC3 (U373cc9) versus control transfected U373 neo. Transcripts upregulated in U373cc9 cells are shown in the first (upper) part of the Table, and transcripts downregulated in U373cc3 versus U373neo are shown in the second part of the Table.

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Additional file 3:

List of genes induced or repressed after UV exposure in U373 clones with or without exogenous CC3. The Table shows expression changes induce by UV in glioblastoma clones. U373neo and U373cc3 cells were exposed to 20 J/m2 UV. RNAs were prepared two hours later. Transcripts induced and repressed by UV are listed; ranking was based on U373neo cells.

Format: XLS Size: 114KB Download file

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