Table 1

Ruffle Summary Statistics

Stain

% of cells with ruffles

Ruffles per cell (+/- S.D.)


Endogenous R-Ras

42 of 51 (82%)

2.9 ± 0.5

with R-Ras siRNA

0 of 30 (0%)

N/A

Cholera Toxin B

29 of 34 (85%)

3.3 ± 0.7

with R-Ras siRNA

2 of 15 (9%)

0.3 ± 0.02

GFP-R-Ras(wt)

150 of 189 (79%)

3.2 ± 0.6

GFP-R-Ras(38V)

191 of 210 (91%)

8.9 ± 1.1

GFP-R-Ras(41A)

5 of 202 (2%)

0.1 ± 0.003


Conklin et al. BMC Cell Biology 2010 11:14   doi:10.1186/1471-2121-11-14

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