Image restoration by deconvolution. A series of Z slices were obtained from MRC5 cells labelled for RPA (in A) or PCNA (in B) in both confocal and STED modes. The images were then restored using the CMLE deconvolution algorithm of Huygens (SVI). Scale bars = 2 μm.
Cseresnyes et al. BMC Cell Biology 2009 10:88 doi:10.1186/1471-2121-10-88