Open Access Research article

The Golgi α-1,6 mannosyltransferase KlOch1p of Kluyveromyces lactis is required for Ca2+/calmodulin-based signaling and for proper mitochondrial functionality

Elena Zanni12, Francesca Farina125, Antonella Ricci3, Patrizia Mancini3, Claudio Frank4, Claudio Palleschi12 and Daniela Uccelletti12*

Author Affiliations

1 Dpt. Developmental and Cell Biology, University LA SAPIENZA, P.le A. Moro,5 00185 Rome, Italy

2 Pasteur Insitute-Fondazione Cenci Bolognetti, LA SAPIENZA, Rome, Italy

3 Dpt. Experimental Medicine, University LA SAPIENZA, Rome, Italy

4 National Centre for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy

5 Institut de Génétique et Microbiologie, UMR8621, Université Paris-Sud, 91405 Orsay Cedex, France

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BMC Cell Biology 2009, 10:86  doi:10.1186/1471-2121-10-86

Published: 14 December 2009

Additional files

Additional file 1:

Cell viability after H2O2 challenge. Indicated strains, grown to exponential phase on YPD medium, were challenged with 20 mM H2O2 for 2 h. The viability was evaluated plating the samples on YPD and was expressed as the CFU percentage of the corresponding untreated cultures. The values were the mean of three independent experiments and showed an SD < 10%.

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