Table 1

Dissociation constants for Tpr interaction with: CRM1, importin β or importin α.

Recombinant Protein

Kd apparent (nM)


CRM1

Too low to measure

CRM1+NES

176 ± 8 (3)

CRM1+NES+RanGTP

83 ± 5 (3)

Importin β

63 ± 5 (3)

Importin β I178D

Too low to measure

Importin α

21.5 ± 1.5 (3)


Data represent the mean ± SD (number of repeats in parentheses) for the apparent dissociation constant

Kd (see legend to Figs. 1 and 2).

Ben-Efraim et al. BMC Cell Biology 2009 10:74   doi:10.1186/1471-2121-10-74

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