Table 1 |
|
|
Dissociation constants for Tpr interaction with: CRM1, importin β or importin α. |
|
|
Recombinant Protein |
Kd apparent (nM) |
|
|
|
|
CRM1 |
Too low to measure |
|
CRM1+NES |
176 ± 8 (3) |
|
CRM1+NES+RanGTP |
83 ± 5 (3) |
|
Importin β |
63 ± 5 (3) |
|
Importin β I178D |
Too low to measure |
|
Importin α |
21.5 ± 1.5 (3) |
|
|
|
|
Data represent the mean ± SD (number of repeats in parentheses) for the apparent dissociation constant Kd (see legend to Figs. 1 and 2). |
|
|
Ben-Efraim et al. BMC Cell Biology 2009 10:74 doi:10.1186/1471-2121-10-74 |
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