GX1-rmhTNFα selectively concentrates at gastric cancer cells. 99Tcm-GX1-rmhTNFα remained in tumor tissue from 2 h to 18 h after injection (A, C), while no such accumulation was seen in the 99Tcm-rmhTNFα group (B, D). Tumors are indicated by arrows. (E) Positive staining of CD31 in tumor vasculature (200×). (F) FITC-labeled GX1-rmhTNFα bound specifically to tumor vasculature (200×). (G) GX1-rmhTNFα colocalized with CD31 in tumor vasculature (200×). Arrow indicates a positively stained microvessel.
Chen et al. BMC Cell Biology 2009 10:63 doi:10.1186/1471-2121-10-63