Table 1

Accumulated insulin, C-peptide and pro-insulin release and insulin content.

VGA

APM

CPR

hBeta-cells


Insulin release (ng/ngDNA)

5 × 10-2 ± 1 × 10-2

2.5 × 10-2 ± 3 × 10-3

9 × 10-3 ± 1 × 10-3

9 × 10-5 ± 1 × 10-5

Insulin content (ng/ng DNA)

<3 × 10-7

<3 × 10-7

<3 × 10-7

3 × 10-4 ± 1 × 10-4

Pro-Insulin release (pmol/ng DNA)

8 × 10-4 ± 2 × 10-4

3 × 10-4 ± 3 × 10-5

3 × 10-4 ± 1 × 10-5

N.D.

C-peptide release (ng/ng DNA)

5 × 10-2 ± 1 × 10-2

5 × 10-2 ± 1 × 10-2

5 × 10-2 ± 1 × 10-2

5 × 10-2 ± 1 × 10-2

Glucose-induced insulin secretion (Stimulation Index)a

1

1

1

>3


a Stimulation Index = Insulin secretion (20 mM glucose): Insulin release (2.8 mM glucose)

N.D.: not detected

Labriola et al. BMC Cell Biology 2009 10:49   doi:10.1186/1471-2121-10-49

Open Data