Validation of parasite growth inhibition measurement by known antimalarials. IC50 values for 3D7 parasite cultures treated with chloroquine (A) and artemesinin (B) were calculated using images obtained by the Pathway HT and compared to the classical SYBR Green assay. C) IC50 values determined with our high-content assay using fluorometric RNA dye 132A for parasite chloroquine sensitive 3D7 and chloroquine resistant Dd2 strains.
Cervantes et al. BMC Cell Biology 2009 10:45 doi:10.1186/1471-2121-10-45