Perinuclear localization of centrosome proteins persists after fusion of myoblasts into myotubes, and in adult mouse muscle. (A) Myotube of fused C2C12 cells in culture. Immunofluorescence of PCM-1 (red); DNA is stained in blue. (B) Cryosection through leg muscle from a mouse. Left: immunofluorescence of PCM-1. Middle: nuclei, stained with the DNA marker DAPI. Right: phase contrast image, showing the striations of the muscle tissue. Bar, 10 μm.
Srsen et al. BMC Cell Biology 2009 10:28 doi:10.1186/1471-2121-10-28