Figure 6.
Transcription factor activity identified in silico and in vivo. A) Example of TREs overrepresented in first ontological cluster. Several genes (vertical)
share common TREs (horizontal), highlighted by red. Results were filtered to show
only TREs overrepresented at p < 0.05 and FDR < 0.3. TREs in bold show a significant
increase in expression on crECM compared to plastic confirmed by transcription factor
array experiment. B) Example of changes in binding activity of a few TFs on plastic
and crECM. Gray/black bars show binding activity on plastic/crECM, respectively.
Dozmorov et al. BMC Bioinformatics 2008 9(Suppl 9):S4 doi:10.1186/1471-2105-9-S9-S4 |