Figure 7.

Analysis of the predictions on the stabilizing mutations. Accuracy [Q] of SVM-3D9 (gray histograms), of SVM-WIN31 (dotted histograms) and database frequencies [DB] (white histograms) as a function of the mutated versus wild-type residues for the stabilizing mutations. The data are computed on the experimental database after symmetrizing according the thermodynamic assumption (see Methods).