This article is part of the supplement: Highlights from the Fourth International Society for Computational Biology (ISCB) Student Council Symposium
Poster presentation
Robust consensus computation
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* Corresponding author: Tobias Rausch rausch@mi.fu-berlin.de
1 International Max Planck Research School for Computational Biology and Scientific Computing, Ihnestr. 63-73, 14195 Berlin, Germany
2 Algorithmische Bioinformatik, Institut für Informatik, Takustr. 9, 14195 Berlin, Germany
BMC Bioinformatics 2008, 9(Suppl 10):P4 doi:10.1186/1471-2105-9-S10-P4
Published: 30 October 2008First paragraph (this article has no abstract)
High-throughput sequencing technologies with short read data pose a new challenge to the current three-phase assembly methodology: Overlap-Phase, Layout-Phase, and Consensus-Phase. We describe a new consensus method that is robust in the face of high coverage, shorter reads, and genomic variation.