Table 12

KEGG Pathways and total numbers of ORFs and reactions added to the aber model from KEGG and not included in IFF708

Kegg Pathway

Number of Reactions

Number of ORFs

Citrate cycle (TCA cycle)

8

12

Tryptophan metabolism

5

2

Bile acid biosynthesis

1

2

Fatty acid biosynthesis (path 1)

32

1

One carbon pool by folate

1

1

Biotin metabolism

5

1

Selenoamino acid metabolism

10

3

Folate biosynthesis

2

1

Purine metabolism

33

71

Pentose phosphate pathway

1

1

Nicotinate and nicotinamide metabolism

2

1

Fatty acid metabolism

4

1

Lysine degradation

7

2

Propanoate metabolism

1

1

Glycine, serine and threonine metabolism

17

12

C5-Branched dibasic acid metabolism

6

2

Pyruvate metabolism

8

5

Methionine metabolism

10

3

Alanine and aspartate metabolism

4

4

Ubiquitin mediated proteolysis

1

14

Sulfur metabolism

8

1

Nitrogen metabolism

2

2

Glutamate metabolism

4

4

Aminosugars metabolism

2

1

N-Glycans biosynthesis

8

14

Starch and sucrose metabolism

3

4

Pentose and glucuronate interconversions

2

1

Glycerolipid metabolism

10

3

gamma-Hexachlorocyclohexane degradation

7

7

Phenylalanine, tyrosine and tryptophan biosynthesis

2

5

No Pathway Annotation

50

153

RNA polymerase

5

31

Lysine biosynthesis

5

1

Oxidative phosphorylation

3

26

Butanoate metabolism

10

5

Fructose and mannose metabolism

1

1

Pyrimidine metabolism

29

68

1,4-Dichlorobenzene degradation

3

1

Phosphatidylinositol signaling system

1

10

DNA polymerase

5

18

Porphyrin and chlorophyll metabolism

2

1

Arginine and proline metabolism

1

2

Cysteine metabolism

11

3

Galactose metabolism

1

1

Pantothenate and CoA biosynthesis

6

2

Aminoacyl-tRNA biosynthesis

18

27

Glycolysis / Gluconeogenesis

12

8

Valine, leucine and isoleucine biosynthesis

13

10

Riboflavin metabolism

5

7

Whelan and King BMC Bioinformatics 2008 9:97   doi:10.1186/1471-2105-9-97