Table 7 |
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|
Shortest Path between GATA3 and other Genes in the Top 22 Pathways (without overlap with GATA3 pathway) |
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|
GATA3 and |
Distance (gene steps) |
Number of links with the shortest distance* |
Genes with literature related to breast cancer* |
|
|
|||
|
ESR1 (in pathway cluster) |
2 |
6 [MUC1, SMAD8, IKK-alpha, HDAC4, HNF3-alpha, GATA-1] |
7 |
|
EGFR |
2 |
1 [MUC1] |
6 (subset of the 7 above) |
|
IKBKB |
2 |
1 [IKK-alpha] |
0 |
|
IFNAR |
3 |
||
|
GFRA1 |
3 |
||
|
IGF1 |
3 |
||
|
ATP7B |
3 |
||
|
VAV3 |
3 |
||
|
COX7c |
3 |
||
|
B3GNT6 |
3 |
||
|
MYCL1 |
3 |
||
|
ACACB |
3 |
||
|
UQCRH |
3 |
||
|
LYN |
3 |
||
|
ACTN1 |
3 |
||
|
IL6ST |
3 |
||
|
STC2 |
4 |
||
|
PDXK |
4 |
||
|
CFLAR |
4 |
||
|
BBOX1 |
4 |
||
|
TARS |
5 |
||
|
SSH3 |
5 |
||
|
NDUFA9 |
6 |
||
|
HMGCL |
6 |
||
|
ABAT |
6 |
||
|
DAZAP2 |
Infinity |
||
|
|
|||
|
*shown only for the shortest distance |
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|
Pang and Zhao BMC Bioinformatics 2008 9:87 doi:10.1186/1471-2105-9-87 |
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