Table 7

Shortest Path between GATA3 and other Genes in the Top 22 Pathways (without overlap with GATA3 pathway)

GATA3 and

Distance (gene steps)

Number of links with the shortest distance*

Genes with literature related to breast cancer*


ESR1 (in pathway cluster)

2

6 [MUC1, SMAD8, IKK-alpha, HDAC4, HNF3-alpha, GATA-1]

7

EGFR

2

1 [MUC1]

6 (subset of the 7 above)

IKBKB

2

1 [IKK-alpha]

0

IFNAR

3

GFRA1

3

IGF1

3

ATP7B

3

VAV3

3

COX7c

3

B3GNT6

3

MYCL1

3

ACACB

3

UQCRH

3

LYN

3

ACTN1

3

IL6ST

3

STC2

4

PDXK

4

CFLAR

4

BBOX1

4

TARS

5

SSH3

5

NDUFA9

6

HMGCL

6

ABAT

6

DAZAP2

Infinity


*shown only for the shortest distance

Pang and Zhao BMC Bioinformatics 2008 9:87   doi:10.1186/1471-2105-9-87

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