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Open AccessMethodology article

Use of normalization methods for analysis of microarrays containing a high degree of gene effects

Terri T Ni1 email, William J Lemon4 email, Yu Shyr2,3 email and Tao P Zhong1 email

Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA

Division of Cancer Biostatistics, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA

Department of Statistics, National Cheng Kung University, Taiwan, ROC

Academic Programs, Missouri Tech, St. Louis, MO 63132, USA

author email corresponding author email

BMC Bioinformatics 2008, 9:505doi:10.1186/1471-2105-9-505

Published: 28 November 2008

Additional files

Additional file 1:

Additional data analysis results. figures illustrating accuracy of normalization in the analysis of linear simulated data and gene effect conditions before and at the NVSA performance break-down.

Format: PDF Size: 330KB Download file

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