Table 4

Best overall mutants obtained for each case study

CASE STUDY

BPCY

List of knockouts

S. cerevisiae, succinate, aerobic

0.05398

PGI1_1, PGI1_2, FBP1, PDC6, ADH4, SDH3_2, AAH1_1, URH1_1, U30_, MET3, ALD4_2, GSH1, U103_, YER053C, CTP1_1*

E. coli, lactate, aerobic

0.39850

ALCD19, DRPA, GLYCDx, F6PA, TPI, LDH_D2, EDA, TKT2, LDH_D-

E. coli, lactate, anaerobic

0.25527

FRD3, GART, ADHEr *

E. coli, succinate, aerobic

0.35785

MALS, ORNDC, FUM, GLYCL, GHMT2, ADPT, DCYTD, DUTPDP, URIDK2r, NTD8, PUNP1, THD2, GND, PFL, SUCFUMt *

This table shows the list of knockouts in the best solution found in all the runs of both algorithms. In the rows marked with *, other solutions with the same BPCT exist; the one with less knockouts was selected (see Additional file 2 for the complete list)

Rocha et al. BMC Bioinformatics 2008 9:499   doi:10.1186/1471-2105-9-499