Table 2

High SGPC pairs, prostate

Affy HGU95 ID
Gene symbol
KEGG ID
Pathway description
SGPC
p

39637_at
SLC26A2
00300
Lysine biosynthesis
0.928
<1e-04
39799_at
FABP5
00300
Lysine biosynthesis
0.829
<1e-04
39794_at
USP8
00300
Lysine biosynthesis
0.824
<1e-04
40773_at
MYL5
00300
Lysine biosynthesis
0.82
<1e-04
40027_at
ATP5S
00300
Lysine biosynthesis
0.814
1e-04
32001_s_at
PCSK6
04742
Taste transduction
0.807
<1e-04
32001_s_at
PCSK6
00600
Sphingolipid metabolism
0.799
<1e-04
32001_s_at
PCSK6
05110
Cholera – Infection
0.798
1e-04
41275_at
E2F5
00300
Lysine biosynthesis
0.798
3e-04
32001_s_at
PCSK6
00604
Glycosphingolipid biosynthesis – ganglioseries
0.786
<1e-04
32001_s_at
PCSK6
00061
Fatty acid biosynthesis
0.771
<1e-04
32001_s_at
PCSK6
00290
Valine, leucine and isoleucine biosynthesis
0.771
<1e-04
39945_at
FAP
00300
Lysine biosynthesis
0.768
6e-04
32001_s_at
PCSK6
03060
Protein export
0.765
<1e-04
38571_at
FGFR1OP
04740
Olfactory transduction
0.76
<1e-04
32001_s_at
PCSK6
00190
Oxidative phosphorylation
0.751
<1e-04
38571_at
FGFR1OP
00440
Aminophosphonate metabolism
0.749
<1e-04
40176_at
TRIM27
00625
Tetrachloroethene degradation
0.742
<1e-04
38571_at
FGFR1OP
04630
Jak-STAT signaling pathway
0.739
<1e-04
38571_at
FGFR1OP
04020
Calcium signaling pathway
0.737
<1e-04
38571_at
FGFR1OP
00150
Androgen and estrogen metabolism
0.734
<1e-04
38571_at
FGFR1OP
04930
Type II diabetes mellitus
0.733
<1e-04
32001_s_at
PCSK6
00930
Caprolactam degradation
0.732
1e-04
38571_at
FGFR1OP
04340
Hedgehog signaling pathway
0.73
3e-04
38571_at
FGFR1OP
00860
Porphyrin and chlorophyll metabolism
0.728
2e-04
32001_s_at
PCSK6
00903
Limonene and pinene degradation
0.728
<1e-04
38571_at
FGFR1OP
04650
Natural killer cell mediated cytotoxicity
0.724
2e-04
38571_at
FGFR1OP
04810
Regulation of actin cytoskeleton
0.721
1e-04
38571_at
FGFR1OP
01510
Neurodegenerative Disorders
0.721
<1e-04
40925_at
C7orf44
00300
Lysine biosynthesis
0.72
1e-04
38571_at
FGFR1OP
04660
T cell receptor signaling pathway
0.719
<1e-04
861_g_at
MSH2
03020
RNA polymerase
0.713
<1e-04
38571_at
FGFR1OP
00903
Limonene and pinene degradation
0.712
<1e-04
38571_at
FGFR1OP
00290
Valine, leucine and isoleucine biosynthesis
0.711
2e-04
38571_at
FGFR1OP
04920
Adipocytokine signaling pathway
0.71
<1e-04
38571_at
FGFR1OP
00930
Caprolactam degradation
0.708
0.0013
32001_s_at
PCSK6
00471
D-Glutamine and D-glutamate metabolism
0.707
<1e-04
38571_at
FGFR1OP
00140
C21-Steroid hormone metabolism
0.706
1e-04
38571_at
FGFR1OP
00562
Inositol phosphate metabolism
0.704
<1e-04
38571_at
FGFR1OP
00604
Glycosphingolipid biosynthesis – ganglioseries
0.702
7e-04

High-ranking gene-pathway pairs in prostate data, sorted by descending SGPC. Affymetrix ID, gene symbol, KEGG pathway ID, and pathway description are given, along with the GPC scores; p values are based on a permutation test with 104 resamplings.

Braun et al. BMC Bioinformatics 2008 9:488   doi:10.1186/1471-2105-9-488