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Open AccessMethodology article

Modifying the DPClus algorithm for identifying protein complexes based on new topological structures

Min Li1 email, Jian-er Chen1,2 email, Jian-xin Wang1 email, Bin Hu1 email and Gang Chen1 email

School of Information Science and Engineering, Central South University, Changsha, Hunan 410083, PR China

Department of Computer Science, Texas A&M University, College Station, Texas 77843, USA

author email corresponding author email

BMC Bioinformatics 2008, 9:398doi:10.1186/1471-2105-9-398

Published: 25 September 2008

Additional files

Additional file 1:

P-values for the predicted clusters with size ≥ 6 generated using Tin = 0.9 and Tin = 0.6. The data provided represent the statistical analysis of the predicted clusters. P-value is calculated for each predicted cluster and a function category is assigned to it when the minimum P-value occurs. When Tin = 0.9, there are 132 clusters (size ≥ 6) generated by IPCA. When Tin = 0.6, there are 443 clusters (size ≥ 6) generated by IPCA.

Format: XLS Size: 168KB Download file

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Additional file 2:

Functional annotation for a predicted cluster of 10 proteins. This file provides a cluster which is composed of ten proteins: YGL173c, YOL149w, YBL026w, YCR077c, YJR022w, YER112w, YER146w, YDR378c, YNL147w, and YLR438c-a. The functional annotations for each protein in the cluster are listed in this file.

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