Table 2

Parameters used to generate simulated data for the 5 cases tested


Class T
Class N



Number of Samples
Mean
Stdev*
Number of Samples
Mean
Stdev*

Case 1
10
250
50
10
100
30
Case 2
10
250
100
10
200
100
Case 3
3
900
100
10
100
30

7
100
50



Case 4
3
400
50
5
100
30

3
300
50
5
130
30

4
100
30



Case 5
3
900
100
7
100
30

7
100
50
3
400
100

* Standard deviation

Parameters for the normal distributions used are indicated only for the 1000 differentially expressed genes. Data for the 9000 non differentially expressed genes is simulated using a mean of 100 and standard deviation of 30. Expression levels of samples for each case (for a representative example) are indicated in Figure 2A in the form of a heatmap

Gadgil BMC Bioinformatics 2008 9:380   doi:10.1186/1471-2105-9-380