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Parameters used in the Population Proportion Ranking Method |
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| Parameter |
Description |
Remark |
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| CTN |
Ratio cutoff for inter-class ratios |
Chosen based on the required magnitude of difference in expression between the two classes |
| CTT, CNN |
Ratio cutoff for intra-class ratios |
Chosen based on allowable heterogeneity in expression within a class |
| pcutoff |
Significance value cutoff for significance of difference between the proportions of inter-class and intra-class populations greater than respective ratio cutoffs |
Chosen based on required stringency in difference between the proportions of inter-class and intra-class populations greater than respective ratio cutoffs |
Gadgil BMC Bioinformatics 2008 9:380 doi:10.1186/1471-2105-9-380 |
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