BMC Bioinformatics

official impact factor 3.03

Open Access Highly Access Methodology article

Parameter estimation for robust HMM analysis of ChIP-chip data

Peter Humburg1,2*, David Bulger1 and Glenn Stone2

Author Affiliations

1 Department of Statistics, Macquarie University, North Ryde, NSW 2109, Australia

2 CSIRO Mathematical and Information Sciences, North Ryde, NSW 2113, Australia

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BMC Bioinformatics 2008, 9:343 doi:10.1186/1471-2105-9-343

Published: 18 August 2008

Additional files

Additional file 1:

False negative probe calls resulting from different models. For any given cut-off TileMap produces more false negatives than the Baum-Welch and Viterbi trained models.

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Additional file 2:

False positive probe calls resulting from different models. For any given cut-off TileMap produces fewer false positives than the Baum-Welch and Viterbi trained models.

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Additional file 3:

Origin of isolated enriched probes in dataset I. The isolated enriched probes identified in dataset I by the Baum-Welch model originate from enriched regions identified by the Baum-Welch model in the real data. Two out of three probes are located close to enriched regions identified by TileMap.

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