Figure 4.

ROC₅₀ scores of various methods for remote homolog detection at the superfamily level. The mean ROC₅₀ score of NMF feature (0.66) is better than those of original PPA (0.49). At > 0.90 ROC₅₀ scores, 52% of proteins with NMF features correctly detect remotely related proteins, whereas by using original PPA features only 28% of proteins detect remote homologs and that of HHsearch is 39%.