|
Selected features |
|
| Feature |
Annotation |
|
|
|
| is_HLA |
Whether the protein containing the SAP belongs to HLA family [18]. |
| nor_diff_freq |
Normalized difference between mutant-type residue frequency and wild-type residue frequency. |
| DAYM780301 |
Log odds matrix for 250 PAMs [27]. The value between two amino acids shows how often one amino acid replaces another one in evolution. |
| FEND850101 |
Structure-Genetic matrix [28]. This matrix takes into account of the structural similarities of amino acids and the genetic code. |
| ZHAC000105 |
Environment-dependent residue contact energies [29]. The residue contact energies in different structural environment. |
| HENS920103 |
BLOSUM80 substitution matrix [30]. The value between two amino acids is defined based on the log likelihood of one amino acid substitutes the other by chance in sequence alignment. |
| NAKH900106 |
Normalized composition from animal [31]. Normalized residue composition calculated from animal mitochondrial proteins. |
| metal_seq_neibor |
The sequence distance between the SAP site and its nearest residue holding the functional site with Feature Key of METAL [18]. |
| MIYS850103 |
Quasichemical energy of interactions in an average buried environment [32]. |
| modres_seq_neibor |
The sequence distance between the SAP site and its nearest residue holding the functional site with Feature Key of MOD_RES [18]. |
Hu and Yan BMC Bioinformatics 2008 9:297 doi:10.1186/1471-2105-9-297 |
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