BMC Bioinformatics

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Precise detection of rearrangement breakpoints in mammalian chromosomes

Claire Lemaitre*, Eric Tannier, Christian Gautier and Marie-France Sagot

BMC Bioinformatics 2008, 9:286 doi:10.1186/1471-2105-9-286

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Proceedings   Open Access

Detection of gene expression changes at chromosomal rearrangement breakpoints in evolution

Adriana Muñoz, David Sankoff BMC Bioinformatics 2012, 13(Suppl 3):S6 (21 March 2012)

Proceedings   Open Access

The rise and fall of breakpoint reuse depending on genome resolution

Oliver Attie, Aaron E Darling, Sophia Yancopoulos BMC Bioinformatics 2011, 12(Suppl 9):S1 (5 October 2011)

Research article   Open Access Highly Accessed

Analysis of fine-scale mammalian evolutionary breakpoints provides new insight into their relation to genome organisation

Claire Lemaitre, Lamia Zaghloul, Marie-France Sagot, Christian Gautier, Alain Arneodo, Eric Tannier, Benjamin Audit BMC Genomics 2009, 10:335 (24 July 2009)

Mammalian evolutionary breakpoints occur frequently in GC-rich intergenic regions characteristic of high-transcriptional activity and replication initiation, suggesting that their distribution is linked to natural selection and a mutational bias due to local open chromatin state.