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An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments

Ari Rantanen*, Juho Rousu, Paula Jouhten, Nicola Zamboni, Hannu Maaheimo and Esko Ukkonen

BMC Bioinformatics 2008, 9:266 doi:10.1186/1471-2105-9-266

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Methodology article   Open Access Highly Accessed

Inferring branching pathways in genome-scale metabolic networks

Esa Pitkänen, Paula Jouhten, Juho Rousu BMC Systems Biology 2009, 3:103 (29 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

ReTrace finds branching pathways in atom-level representations of genome-scale metabolic networks by considering combinations of the shortest linear pathways, scaling better than constraint-based modeling and avoiding shortfalls of graph-theoretic approaches.

Research   Open Access

OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis

Lake-Ee Quek, Christoph Wittmann, Lars K Nielsen, Jens O Krömer Microbial Cell Factories 2009, 8:25 (1 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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