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Open AccessResearch article

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

William S Bush1 email, Todd L Edwards1 email, Scott M Dudek1 email, Brett A McKinney2 email and Marylyn D Ritchie1 email

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, USA

author email corresponding author email

BMC Bioinformatics 2008, 9:238doi:10.1186/1471-2105-9-238

Published: 16 May 2008

Additional files

Additional file 1:

Statistical details of detection, power, and genetic models. The figures and data tables provided show the multi-locus penetrance tables used for each genetic model, the statistical details of the detection and power results, and confidence bounds for the power results.

Format: DOC Size: 1.1MB Download file

This file can be viewed with: Microsoft Word Viewer


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