BMC Bioinformatics

official impact factor 3.03

Open Access Research article

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

William S Bush1, Todd L Edwards1, Scott M Dudek1, Brett A McKinney2 and Marylyn D Ritchie1*

Author Affiliations

1 Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

2 Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, USA

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BMC Bioinformatics 2008, 9:238 doi:10.1186/1471-2105-9-238

Published: 16 May 2008

Additional files

Additional file 1:

Statistical details of detection, power, and genetic models. The figures and data tables provided show the multi-locus penetrance tables used for each genetic model, the statistical details of the detection and power results, and confidence bounds for the power results.

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