Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites

Jill L Wegrzyn^*¹^,3 , Thomas M Drudge^*² , Faramarz Valafar¹^,2 and Vivian Hook³^,4

¹Computational Science Research Center, San Diego State University, San Diego, USA

²Department of Computer Science, San Diego State University, San Diego, USA

³Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, USA

⁴Depts. of Pharmacology, Neuroscience, and Medicine, School of Medicine, Uiversity of California, San Diego, La Jolla, USA

author email corresponding author email* Contributed equally

BMC Bioinformatics 2008, 9:232doi:10.1186/1471-2105-9-232


Published:	8 May 2008

Additional files

Additional file 1:

Negative set of Mammalian AUG, non-ATIS, mRNA Sequences. A set of 500 sequences were selected from Mammalian species that translate with one or more AUG start sites. These sequences were selected from the validated RefSeq database.

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Additional file 2:

Provisional aTIS RefSeq mRNA Sequences. The provisional set of sequences were selected both from the annotated provisional non-AUG start sites and conserved non-AUG start sites found in aligned 120 bp fragments containing the alternative start sites from the positive aTIS training set.

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