BMC Bioinformatics

official impact factor 3.03

Open Access Highly Access Research article

Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites

Jill L Wegrzyn1,3, Thomas M Drudge2, Faramarz Valafar1,2* and Vivian Hook3,4*

Author Affiliations

1 Computational Science Research Center, San Diego State University, San Diego, USA

2 Department of Computer Science, San Diego State University, San Diego, USA

3 Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, USA

4 Depts. of Pharmacology, Neuroscience, and Medicine, School of Medicine, Uiversity of California, San Diego, La Jolla, USA

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BMC Bioinformatics 2008, 9:232 doi:10.1186/1471-2105-9-232

Published: 8 May 2008

Additional files

Additional file 1:

Negative set of Mammalian AUG, non-ATIS, mRNA Sequences. A set of 500 sequences were selected from Mammalian species that translate with one or more AUG start sites. These sequences were selected from the validated RefSeq database.

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Additional file 2:

Provisional aTIS RefSeq mRNA Sequences. The provisional set of sequences were selected both from the annotated provisional non-AUG start sites and conserved non-AUG start sites found in aligned 120 bp fragments containing the alternative start sites from the positive aTIS training set.

Format: PDF Size: 26KB Download file

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Open Data