Figure 5.

Performance in predicting likely DE genes (Hsf1p binding) using hsf1 microarray data and conserved motif knowledge. ROC curves for the B statistic with microarray data alone, motif knowledge alone, single parameter M-BISON ("best"), and empirical M-BISON ("empir.") are shown. Both forms of M-BISON significantly outperform data or knowledge alone, with the empirical method yielding the best AUC and pAUC^.2.