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Open AccessMethodology article

NestedMICA as an ab initio protein motif discovery tool

Mutlu Doğruel1 email, Thomas A Down2 email and Tim JP Hubbard1 email

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1HH, UK

Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK

author email corresponding author email

BMC Bioinformatics 2008, 9:19doi:10.1186/1471-2105-9-19

Published: 14 January 2008

Additional files

Additional file 1:

Motifs recovered by NestedMICA and MEME in the single-motif spiking tests, for motif set 2. This file contains a figure showing the second set of test motifs as recovered by the two compared programs, along with their cartesian distances to the original motifs and their MCC values.

Format: PDF Size: 2.2MB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 2:

Motifs recovered by NestedMICA and MEME in the single-motif spiking tests, for motif set 3. This file contains a figure showing the third set of test motifs as recovered by the two compared programs, along with their cartesian distances to the original motifs and their MCC values.

Format: PDF Size: 2.3MB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 3:

Sensitivity and specificity values for the motifs reported by NestedMICA and MEME. This file contains two tables showing sensitivity and specificity values of the compared programs in the single and multiple motif spiking tests.

Format: PDF Size: 294KB Download file

This file can be viewed with: Adobe Acrobat Reader


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