Table 1

Recent methods for protein SCL prediction
Speciality		Tool	Reference

Membrane protein predictor	a	TMHMM	[12]
Both transmembrane helices and signal peptide predictor	a	Phobius	[14]
Signal peptide predictor	a	SignalP	[18]
	a	Predisi	[98]
		Signal peptidase type I cleavage site motif	[41]
Lipoprotein predictor	b	LipoP	[151]
	a	Signal peptidase type II cleavage site motif	[41, 157]
Tat-secreted protein predictor	b	TatP	[86]
	a	Tat-find.v.1.2	[174]
Protein subcellular location classifier	b	Psortb.v.2.0	[17]
	b	CELLO	[20]
	b	Gpos-PLoc	[28]
		Augur	[27]
Minor pathway secreted protein predictor	a	Bagel	[149]
		SecretomeP 2.0	[128]
Mycobacteria protein SCL predictor	b	TBpred	[95]

a, Tools included in the LocateP pipeline b, Tools used for comparison and validation of LocateP
Zhou et al. BMC Bioinformatics 2008 9:173 doi:10.1186/1471-2105-9-173