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Open AccessHighly AccessMethodology article

LocateP: Genome-scale subcellular-location predictor for bacterial proteins

Miaomiao Zhou1 email, Jos Boekhorst1,4 email, Christof Francke1,2 email and Roland J Siezen1,2,3 email

1Centre for Molecular and Biomolecular Informatics, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands

2TI Food and Nutrition, and Kluyver Centre for Genomics of Industrial Fermentation, Wageningen, The Netherlands

3NIZO Food Research, Ede, The Netherlands

4Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands

author email corresponding author email

BMC Bioinformatics 2008, 9:173doi:10.1186/1471-2105-9-173

Published: 27 March 2008

Additional files

Additional file 1:

Flow chart and decision tree of the LocateP pipeline. The different SCL tools used at each decision step are indicated. The different SCLs distinguished are boxed in the middle; "Bacteriocin" signifies bacteriocin-like proteins secreted by non-classical pathways, identified by Bagel. a) all tools agreed, b) all possible hits, c) majority vote, d) 2–3 TM segments and C-terminus detected by LPxTG HMM.

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Additional file 2:

The LocateP predicted N-anchored and secreted proteins with known function in Bacillus subtilis.

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Additional file 3:

The LocateP predicted N-anchored and secreted proteins of unknown function in Bacillus subtilis.

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Additional file 4:

Literature references for other experimental evidence (Yes (O)) listed in additional file 2.

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