Table 3

Accuracy of mRNA extremity predictions.

Splice-Junction Prediction

Poly(A) Prediction

Exact

< 25 nt

< 10 nt

< 100 nt


Sensitivity

48.6%

58.9%

25.2% (1.5)

45.4% (1.2)

Specificity*

96.4%

97.3%


* Tested on all 3789 annotated coding sequences over 1500 nucleotides in length in L. infantum

True positive (sensitivity) and false positive (specificity) rates are depicted for the best splice-junction and poly(A) site prediction methods. Percentages represent the relative amount of hits that score above a statistical threshold derived from empirical data. The values in parentheses are the standard deviation for poly(A) site prediction sensitivities determined by 15 runs of ten fold cross-validation.

Smith et al. BMC Bioinformatics 2008 9:158   doi:10.1186/1471-2105-9-158

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