Sensitivity of secondary structure predictions as a function of alignment posterior probabilities. Sensitivity is defined as TP/(TP + FN) where TP stands for the true positive estimations and FN stands for the false negative estimations. The Viterbi alignments were obtained for all possible homologous pairs in the HOMSTRAD database, the MPD alignments were estimated for the 12 selected families in Table 1.
Miklós et al. BMC Bioinformatics 2008 9:137 doi:10.1186/1471-2105-9-137